Publicaciones (Papers)

P. de la Peña, F. Barros, S. Gascón, S. Ramos and P.S. Lazo.
Primary effects of yeast killer toxin.

Biochem. Biophys. Res. Commun. (1980) 96: 544-550
ISI Impact: 2.78                       Journal position in: Biochemistry & Molecular Biology, 97 out of  295

P.S. Lazo, F. Barros, P. de la Peña and S. Ramos.
Ion gradients as candidates for transmembrane signaling.
Trends Biochem. Sci. (1981) 6: 83-85                 

ISI Impact: 17.08                     Journal position in: Biochemistry & Molecular Biology, 7 out of 295  


F. Barros, P. de la Peña, S. Gascón, S. Ramos and P.S. Lazo.
Cholera toxin induces changes in the ion permeability of intestinal brush border membranes.
Biochim. Biophys. Acta (1981) 644: 143-146

ISI Impact: 2.47                       Journal position in: Biochemistry & Molecular Biology, 97 out of 295  


S. Ramos, F. Barros, P. de la Peña and P.S. Lazo.
Exotoxins which alter electrochemical ion gradients.
Ciencia Biologica (1981) 6 : 25-27

ISI Impact:                               Journal position  


P. de la Peña, F. Barros, S. Gascón, P.S. Lazo and S. Ramos.
Effect of yeast killer toxin on sensitive cells of Saccharomyces cerevisiae.
J. Biol. Chem. (1981) 256: 10420-10425

ISI Impact: 7.19                       Journal position in: Biochemistry & Molecular Biology, 23 out of 295  


P. de la Peña, F. Barros, S. Gascón, S. Ramos and P.S. Lazo.
The electrochemical proton gradient of Saccharomyces. The role of potassium.
Eur. J. Biochem. (1982) 123: 447-453

ISI Impact: 3.24                       Journal position in: Biochemistry & Molecular Biology, 69 out of 295


F. Barros and G.J. Kaczorowski
Mechanisms of Ca++ transport in plasma membrane vesicles  prepared from cultured pituitary cells.II.(Ca++-Mg++) ATPase- dependent Ca++ transport activity.
J. Biol. Chem. (1984) 259: 9404-9410
ISI Impact: 7.19                       Journal position in: Biochemistry
& Molecular Biology, 23 out of 295


J.P. Reeves, C.C. Hale, P. de la Peña, R.S. Slaughter, T. Boulware, J. Froehlich, G.J. Kaczorowski and E. Cragoe.
A model for the sodium-calcium exchange carrier.
Epithelial calcium and phosphate aspects. Progress in clinical and biological research.
F. Bronnei and M.Petulik, Eds. (1984) Vol: 168     Pages: 77-82
Alan R. Liss, New York


S. Ramos, P. de la Peña, E. Valle, L. Bergillos, F. Parra and P. S. Lazo.
Coupling of proton and potassium gradients in yeast.
Environmental regulation of microbial metabolism.

J.S. Kulaev, E.A. Dawes y L.W. Tempst, Eds. (1985) Pages: 351-357               
Academic Press


G.J. Kaczorowski, F. Barros, J.K. Dethmers, M.J. Trumble and E.J. Cragoe Jr.
Inhibition of Na+/Ca++ exchange in pituitary plasma membrane vesicles by analogs of amiloride.
Biochemistry (US) (1985) 24: 1394-1403

ISI Impact: 4.62                       Journal position in: Biochemistry & Molecular Biology, 45 out of 295  


P. Domínguez, F. Barros and P.S. Lazo
The activation of adenylate cyclase from small intestinal epithelium by cholera toxin.
Eur. J. Biochem. (1985) 24: 1394- 1403

ISI Impact: 3.24                       Journal position in: Biochemistry & Molecular Biology, 69 out of 295  


P.S. Lazo, F. Barros, P. Domínguez, A. Rivaya and G. Velasco
Adenylate cyclase from rabbit small intestine: Activation by cholera toxin and interaction with calcium.
Arch. Biochem. Biophys. (1985) 239: 587-594

ISI Impact: 2.49                       Journal position in: Biophysics, 16 out of 57
  


F. Barros, G.M. Katz, G.J. Kaczorowski, R.L. Vandlen and J.P. Reuben
Calcium currents in GH3 cultured pituitary cells under whole cell voltage clamp: Inhibition by voltage dependent potassium currents

Proc. Natl. Acad. Sci. USA (1985) 82: 1108-1112
ISI Impact: 9.82                       Journal position in: Multidisciplinary, 3 out of 62


F. Barros, G.J. Kaczorowski, G.M. Katz, R.L. Vandlen and J.P. Reuben
Electrophysiological techniques in pharmacology
Application of whole-cell voltage clamp in the study of neuroendocrine cells
H. Geller Ed. (1986) Pages: 149-168
Alan R. Liss, NewYork

 

F. Barros, P. Domínguez, G. Velasco and  P.S. Lazo
Na+/H+ exchange is present in basolateral membranes from rabbit small intestine.
Biochem. Biophys. Res. Commun. (1986) 134: 827-834
ISI Impact: 2.78                       Journal position in: Biophysics, 12 out of 57
 


G. Velasco, P. Domínguez, S.B. Shears and P.S. Lazo
Permeability properties of isolated enterocytes from rat small intestine
Biochim. Biophys. Acta (1986) 889: 361-365
ISI Impact: 2.47                       Journal position in: Biochemistry & Molecular Biology, 97 out of 295


G. Velasco, C.F. Iglesias, P. Domínguez, F. Barros, S. Gascón and  P.S.Lazo
Protein kinase C from small intestine epithelial cells.
Biochem. Biophys. Res. Commun. (1986) 139: 875-882 

ISI Impact: 2.78                       Journal position in: Biochemistry & Molecular Biology, 97 out of  295


P. Domínguez, G. Velasco, F. Barros and P.S. Lazo
Intestinal brush border membranes contain regulatory subunits of  adenylate cyclase.
Proc. Natl. Acad. Sci. USA (1987) 84: 6965- 6969

ISI Impact: 9.82                       Journal position in: Multidisciplinary, 3 out of 62
  


P. de la Peña and J. P. Reeves.
Inhibition and activation of sodium-calcium exchange activity by quinacrine.
Amer. J. Physiol. (1987) 252: C24-C29
ISI Impact: 3.077                     Journal position in: Physiology, 9 out of 67  


B.J. Lee, P. de la Peña, J.A. Tobian, M. Zasloff and D. Hatfield.
Unique pathway of expression of an opal suppressor phosphoserine tRNA.
Proc. Natl. Acad. Sci. U.S.A (1987) 84: 6384- 6388                            

ISI Impact: 9.82                       Journal position in: Multidisciplinary, 3 out of 62


P. de la Peña  and  M. Zasloff.
Enhancement of mRNA nuclear transport by promoter elements.
Cell (1987) 50: 613- 619                       

ISI Impact:: 38.68                    Journal position in: Biochemistry & Molecular Biology, 2 out of 295
 

J.C. Lacal, P. de la Peña, J. Moscat, P. García-Barreno and S. Aaronson.
Rapid stimulation of phosphoinositide turnover in Xenopus oocytes by microinjection of the oncogenic H-ras p21 protein.
Science (1987) 238: 533- 536
ISI Impact: 24.38                     Journal position in: Multidisciplinary, 2 out of 62


G. Velasco; M. Prieto, J. Alvarez-Riera, S. Gascón and F. Barros
Characteristics and regulation of a high conductance anion  channel in GBK kidney epithelial cells.
Pflügers Arch. (Eur. J. Physiol.) (1989) 414: 304- 310

ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67  


M.F. Young, D.M. Findlay, P. Domínguez, P.D. Burbelo, C.I. McQuillan, J.B. Kopp, P. Gehron Robey and J.D. Termine
Osteonectin promoter. DNA sequence analysis and S1 endonuclease site potentially associated with transcripcional control in bone cells.
J. Biol. Chem. (1989) 264: 450-456

ISI Impact: 7.19                       Journal position in: Biochemistry & Molecular Biology, 23 out of 295 


M.F. Young, A.A. Day, P. Domínguez, C.I. McQuillan, L.W. Fisher and J.D. Termine
Structure and expression of osteonectin mRNA in human tissue.
Connect. Tissue Res. (1990)  24: 17- 28

ISI Impact: 1.418                     Journal position in: Cell Biology, 86 out of 139  


P. Domínguez, K. Ibaraki, P. Gehron Robey, T.H. Hefferan, J.D. Termine and M.F. Young
The expression of the osteonectin gene is potentially controlled by multiple cis and trans acting elements.
J. Bone Min. Res. (1991) 6: 1127-1136

ISI Impact: 6.47                       Journal position in: Endocrinology, 6 out of 83 


A. Menéndez-Pelaéz, C. Rodríguez and P. Domínguez
5-Aminolevulanate synthase mRNA levels in the Harderian gland of Syrian hamsters: correlation with porphyrion concentrations and regulation by androgens and melatonin.
Mol. Cell. Endocrinol. (1991) 80: 177-182

ISI Impact: 2.342                     Journal position in: Endocrinology, 24 out of 83 


F. Barros; L.G. López-Briones; M. Coca-Prados and C. Belmonte
Detection and characterization of Ca2+-activated K+ channels in transformed cells of human non-pigmented ciliary epithelium.
Curr. Eye Res. (1991) 10: 731- 738     

ISI Impact: 1.26                       Journal position in: Ophthalmology, 15 out of  42 


F. Barros, L.M. Delgado, C. Maciá and P. de la Peña.
Effects of hyphotalamic peptides on electrical activity and membrane currents of "patch perforated" clamped GH3 anterior pituitary cells.
FEBS Lett. (1991)   279: 33- 37

ISI Impact: 3.58                       Journal position in: Biophysics, 10 out of  57 


P. de la Peña, L.M. Delgado, D. del Camino and F. Barros.
Cloning and expression of the thyrotropin-releasing hormone receptor fron GH3 rat anterior pituitary cells.
Biochem. J. (1992)  284: 891- 899

ISI Impact: 3.85                       Journal position in: Biochemistry & Molecular Biology, 57 out of  295 


F. Barros, L.M. Delgado, D. del Camino and  P. de la Peña.
Characteristics and modulation by thyrotropin-releasing hormone of an inwardly-rectifying potassium current in patch-perforated GH3 anterior pituitary cells.
Pflügers Arch. (Eur. J. Physiol.) (1992)  422: 31- 39

ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67


L.M. Delgado, P. de la Peña, D. del Camino and F. Barros.
Okadaic acid and calyculin A enhance the effect of thyrotropin-releasing hormone on GH3 rat anterior pituitary cells.
FEBS Lett. (1992) 311: 41-45

ISI Impact: 3.58                       Journal position in: Biophysics, 10 out of  57


P. de la Peña, L.M. Delgado, D. del Camino and F. Barros.
Two isoforms of the thyrotropin-releasing hormone receptor generated by alternative splicing have indistinguishable functional properties.
J. Biol. Chem. (1992)  267: 25703- 25708
ISI Impact: 7.19                       Journal position in: Biochemistry & Molecular Biology, 23 out of 295  


A. Menéndez-Peláez, M.J. Rodríguez-Colunga, C. Rodriguez, D. Tolivia and P. Domínguez
Effects of human chorionic gonadotropin and progesterone administration on porphyrin biosynthesis and histology of the Harderian glands in male and female Syrian hamsters.
Biol. Reprod. (1992) 47: 307- 315
ISI Impact: 3.327                     Journal position in: Reproductive Biology, 3 out of 19  


F. Barros, G. Mieskes, D. del Camino and P. de la Peña.
Protein phosphatase 2A reverses inhibition of inward rectifying potassium currents by thyrotropin-releasing hormone in GH3 pituitary cells.
FEBS Lett. (1993)   336: 433- 439        
ISI Impact: 3.58                       Journal position in: Biophysics, 10 out of  57


F. Barros, J. Villalobos, J. García-Sancho, D. del Camino and P. de la Peña.
The role of the inward rectifying potassium current in resting potential and thyrotropin-releasing hormone-induced changes in cell excitability of GH3 rat anterior pituitary cells.
Pflügers Arch. (Eur, J. Physiol.) (1994)  426: 221- 230
ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67


P. Domínguez, I. Antolín, J.A. Boga, H. Uría and A. Menéndez-Peláez
Androgen regulation of gene expression in the Syriam hamster Harderian gland.
Mol. Cell. Endocrinol. (1994) 106: 81- 89
ISI Impact: 2.342                     Journal position in: Endocrinology, 24 out of 83


P. Domínguez
Cloning of a Syriam hamster cDNA related to sexual dimorphism. Establishment of a new family of proteins
FEBS Lett. (1995) 376: 257-261
ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67


P. de la Peña, D. del Camino, L.A. Pardo, P. Domínguez and F. Barros.
Gs couples thyrotropin-releasing hormone receptors expressed in Xenopus oocytes to phospholipase C.
J. Biol. Chem. (1995) 270: 3554-3559  
ISI Impact: 7.19                       Journal position in: Biochemistry & Molecular Biology, 23 out of 295


F. Barros, D. del Camino, L.A. Pardo and P. de la Peña.
Caffeine enhancement of electrical activity through direct blockade of inward rectifying potassium currents in GH3 rat anterior pituitary cells.
Pflügers Arch. (Eur. J. Physiol.) (1996)  431: 443- 451        
ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67  


P. Domínguez, I. Antolín, F. Prieto and A. Menéndez-Peláez
Isolation and identification of sex-specific cDNA clones from Syriam hamsters Harderian gland.
Microsc. Res. Tech. (1996) 34: 111-117
ISI Impact: 0.765                     Journal position in: Microscopy, 6 out of  9  


B. Varriale, J. Alvarez, F. Prieto and P. Domínguez
Hormonal regulation of FHG22 mRNA in Syrian hamster Harderian glands: role of estradiol.
Mol. Cell. Endocrinol. (1996) 124: 87-96
ISI Impact: 2.342                     Journal position in: Endocrinology, 24 out of 83


D. del Camino, F. Barros, L.A. Pardo and P. de la Peña.
Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III.
Biochemistry (US)   (1997) 36: 3308- 3318
ISI Impact: 4.62                       Journal position in: Biochemistry & Molecular Biology, 45 out of  295


F. Barros, D. del Camino, L.A. Pardo, T. Palomero, T. Giráldez and  P. de la Peña.
Demonstration of an inwardly rectifying potassium current component modulated by thyrotropin-releasing hormone and caffeine in GH3 rat anterior pituitary cells.
Pflügers Arch. (Eur. J. Physiol.) (1997)  435: 119- 129
ISI Impact: 2.529                     Journal position in: Physiology, 14 out of  67


T. Palomero, F. Barros, D. del Camino, C.G. Viloria and P. de la Peña.
A G-protein bg dimer-mediated pathway contributes to mitogen-activated protein kinase by thyrotropin-releasing hormone receptors in transfected COS-7 cells.
Mol. Pharmacol. (1998)  53: 613- 622  
ISI Impact: 5.428                     Journal position in: Pharmacology, 6 out of 178 


T. Xu, P. Bianco, L.W. Fisher, G. Longenecker, E. Smith, S. Goldstein, J. Bonadio, A. Boskey, A.M. Heegaard, B. Sommer, K. Satomura, P. Domínguez, Ch. Zhao, A.B. Kulkarni, P.G. Robey and M.Y. Young
Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice.
Nat. Genet. (1998) 20: 78-82
ISI Impact: 40.36                     Journal position in: Genetics, 1 out of 103


F. Barros, D. Gómez-Varela, C.G. Viloria, T. Palomero, T. Giráldez and P. de la Peña.
Modulation of human-erg channel gating by activation of a G protein-coupled receptor and protein kinase C.
J. Physiol. (Lond.) (1998) 511: 333- 346
ISI Impact: 4.72                       Journal position in: Physiology, 6 out of 67


M. Mellado, T. Fernández-Agulló, J.M. Rodriguez-Frade, M. García San Frutos, P. de la Peña, C. Martínez-A and E. Montoya.
Expression analysis of the thyrotropin-releasing hormone receptor (TRH-R) in the immune system using agonist anti-TRH monoclonal antibodies.
FEBS Lett. (1999)   451: 308-314                         
ISI Impact: 3.58                       Journal position in: Biophysics, 10 out of  57


P. de la Peña and F. Barros
Functional expression of G-protein-coupled receptors in Xenopus laevis oocytes.
Microinjection. Methods and tools in biosciences and medicine.
J.C. Lacal, R. Perona and J. Feramisco, Eds. (1999) Pages: 199-210
Birkhäuser Verlag


C.G. Viloria, F. Barros, T. Giráldez, D. Gómez-Varela and P. de la Peña.
Differential effects of N-terminus distal and proximal domains in regulation of human-erg potassium channel gating.
Biophys. J. (2000) 79: 231- 246
ISI Impact: 4.46                       Journal position in: Biophysics, 10 out of 66


T. Esposito, E. Astore, P. Domínguez, G. Chieffi and B. Varriale
Sequence analysis and androgen regulation of MHG07 (Male Harderian Gland) mRNA in male hamster Harderian gland.
Gen. Comp. Endocrinol. (2000) 119: 132- 139
ISI Impact: 1.83                       Journal position in: Endocrinology, 39 out of 83


J. Alvarez, J. Viñas, J.M. Martín Alonso, J.P. Albar, K. Ashman and P. Domínguez
Characterization and cloning of two isoforms of heteroglobin, a novel heterodimeric glycoprotein of the secretoglobin-uteroglobin family showing tissue-specific and sex differential expression.
J. Biol. Chem. (2002) 277: 233- 242
ISI Impact: 7.19                       Journal position in: Biochemistry & Molecular Biology, 23 out of 295


T. Giráldez, P. de la Peña, D. Gómez-Varela and F. Barros.
Correlation between electrical activity and intracellular calcium oscillations in GH3 rat anterior pituitary cells.
Cell Calcium (2002) 31: 65- 78
ISI Impact: 3.28                       Journal position in: Cell Biology, 51 out of 153


D. Gómez-Varela, P. de la Peña, J. García, T. Giráldez and F. Barros.
Influence of amino terminal structures on kinetic transitions between several closed and open states in human-erg potassium channel.
J. Membr. Biol. (2002) 187: 117- 133   
ISI Impact: 2.44                       Journal position in: Physiology, 26 out of 73


D. Gómez-Varela, T. Giráldez, P. de la Peña, S.G. Dupuy, D.G. Manso and F. Barros.
Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells.
J. Physiol. (Lond). (2003) 547: 913- 929
ISI Impact: 4.35                       Journal position in: Physiology, 7 out of 74


P. Miranda, P. de la Peña, D. Gómez-Varela and F. Barros.
Role of BK potassium channels shaping action potentials and the associated [Ca2+]i  oscillations in GH3 rat anterior pitutary cells.
Neuroendocrinology (2003) 77: 162- 176
ISI Impact: 2.84                       Journal position in: Endocrinology, 32 out of 88


D. Gómez-Varela, F. Barros, C.G. Viloria, T. Giráldez, D.G. Manso, S.G. Dupuy, P. Miranda and  P. de la Peña.
Relevance of the proximal domain in the amino terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor. FEBS Lett. (2003) 535: 125- 130

ISI Impact: 3.6                         Journal position in: Biophysics, 10 out of  66



P. Miranda, T. Giráldez, P. de la Peña, D.G. Manso, C. Alonso-Ron, D. Gómez-Varela, P. Domínguez and F. Barros
Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells.
J. Physiol. (Lond.)   (2005) 566: 717-736
ISI Impact: 4.27                       Journal position in: Physiology, 10 out of  75


P. Miranda, D.G. Manso, F. Barros, L. Carretero, T.E. Hughes, C. Alonso-Ron, P. Domínguez and  P. de la Peña.
FRET with multiply labeled HERG K+ channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains.
Biochim. Biophys. Acta – Mol. Cell. Res. (2008) 1783: 1681- 1699     
ISI Impact: 6.9                         Journal position in: Biochemistry & Molecular Biology, 29 out of  262


C. Alonso-Ron, P. De la Peña, P. Miranda, P. Domínguez and F. Barros
Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.
Biophys. J. (2008) 94: 3893-3911
ISI Impact: 4.75                       Journal position in: Biophysics, 8 out of  66


T. Esposito, P. Domínguez and B. Varriale
Hormonal regulation and characterisation of the aldehyde oxidase-like gene of hamster harderian gland.
J. Steroid Biochem. Mol. Biol. (2008) 112: 157-163
ISI Impact: 2.88                       Journal position in: Biochemistry & Molecular Biology, 138 out of  286


C. Alonso-Ron, F. Barros, D. G. Manso, D. Gómez-Varela, P. Miranda, L. Carretero, P. Domínguez and P. de la Peña
Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor.
Pflügers Arch. (Eur. J. Physiol.) (2009)  457: 1237-1252    
ISI Impact: 3.842                     Journal position in: Physiology, 15 out of  78


P. de la Peña, C. Alonso-Ron, A. Machín, J. Fernández-Trillo, L. Carretero, P. Domínguez and F. Barros
Demonstration of physical proximity between the amino terminus and the S4-S5 linker of the h-ERG potassium channel.
J. Biol. Chem. (2011)  286: 19065-19075
ISI Impact: 4.773                       Journal position in: Biochemistry & Molecular Biology, 66 out of 290


J. Fernández-Trillo, F. Barros, A. Machín, L. Carretero, P. Domínguez and P. de la Peña
Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate h-ERG K+  channel gating.
PLoS ONE (2011)  6: e24674
ISI Impact: 4.411                       Journal position in: Biology, 12 out of 85 


M.J. Mazón, F. Barros, P. de la Peña, J.F. Quesada, A. Escudero, A.M. Cobo, S.I. Pascual-Pascual, E. Gutiérrez-Rivas, E. Guillén, J. Arpa, P. Eraso, F. Portillo and J. Molano
Screening for mutations in Spanish families with myotonia. Functional analysis of novel mutations in CLCN1 gene.
Neuromuscular Disord. (2012)  22: 231-243    
ISI Impact: 2.764                     Journal position in: Clinical Neurology, 66 out of  185


L. Carretero, F. Barros, P. Miranda, J. Fernández-Trillo, A. Machín, P. de la Peña and P. Domínguez
Cell type influences the molecular mechanisms involved in hormonal regulation of  ERG K+  channels.
Pflügers Arch. (Eur. J. Physiol.) (2012)  463: 685-702
ISI Impact: 3.842                       Journal position in: Physiology, 15 out of  78 


F. Barros, P. Dominguez and P. de la Peña
Cytoplasmic domains and voltage-dependent potassium channel gating.
Front. Pharmacol. (2012)  3; 49. DOI: 10.3389/fphar.2012.00049
ISI Impact:  3.802                    Journal position in:  Pharmacology, 49 out of 254


S.T. Menendez, J.P. Rodrigo, S. Alvarez-Teijeiro, M.A. Villaronga, E. Allonca, A. Vallina, A. Astudillo, F. Barros, C. Suarez and M. Garcia-Pedrero
Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas.
Modern Pathol. (2012) 25: 1069-1078
ISI Impact: 4.176                     Journal position in: Pathology, 12 out of 76  


F. Barros, P. Dominguez, A. Machin and P. de la Peña
hERG: Un canal de potasio implicado en el ritmo cardíaco y mucho más.
SICI Consolider, artículo divulgativo. En https://sici.umh.es; Marzo 2012.  


B. Ponsati, C. Carreño, V. Curto-Reyes, B. Valenzuela, M.J. Duart, W. Van Den Nest, O. Cauli, B. Beltran, J. Fernandez, F. Borsini, A. Caprioli, S. Di Serio, M. Veretchy, A. Baamonde, L. Menendez, F. Barros, P. de la Peña, R. Borges, V. Felipo, R. Planells-Cases and A. Ferrer-Montiel
An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflamatory and neuropathic pain.
J. Pharmacol. Exp. Ther. (2012)  341: 634-645
ISI Impact: 4.017                    Journal position in: Pharmacology & Pharmacy, 40 out of 252


P. de la Peña, A. Machín, J. Fernández-Trillo, P. Domínguez and F. Barros
Mapping of interactions between the amino and carboxy termini and the channel core in hERG K+ channels.
Biochem. J. (2013)  451: 463-474
ISI Impact: 4.897                    Journal position in: Biochemistry & Molecular Biology, 61 out of 290


P. de la Peña, A. Machín, J. Fernández-Trillo, P. Domínguez and F. Barros
Interactions between the N-terminal tail  and the gating  machinery of hERG  K+ channels both in closed and open/inactive states.
Pflugers Arch. – Eur. J. Physiol (2015) 467: 1747-1756
ISI Impact: 4.101                    Journal position in: Physiology, 13 out of 83


E. Lörinczi, J.C. Gómez-Posada, P. de la Peña, A. Tomczak, J. Fernández-Trillo, U. Leipscher, F. Barros and L.A. Pardo
Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.
Nat. Commun. (2015) 6: 6672. DOI: 10.1038/ncomms7672
ISI Impact: 11.47                    Journal position in: Multidisciplinary Sciences, 3 out of 62


L. Carretero, P. Llavona, A. López-Hernández, P. Casado, P.R. Cutillas, P. de la Peña, F. Barros and P. Domínguez
ERK and RSK are necessary for TRH-induced inhibition of r-ERG  potassium currents in rat pituitary GH3 cells.
Cell. Signal. (2015) 27: 1720-1730
ISI Impact: 4.471                    Journal position in: Cell Biology, 63 out of 185

 


R. González-Montelongo, F. Barros, D. Alvarez de la Rosa and T. Giráldez
Plasma membrane insertion of epithelial sodium channels occurs with dual kinetics.
Pflugers Arch. – Eur. J. Physiol (2016) 468: 859-870
ISI Impact: 4.101                    Journal position in: Physiology, 13 out of 83



P. de la Peña, P. Domínguez and F. Barros
Gating mechanism of Kv11.1 (hERG) K+ channels without covalent connection between voltage sensor and pore domains.
Pflugers Arch. – Eur. J. Physiol (2018) 470: 517-536
ISI Impact: 4.101                    Journal position in: Physiology, 13 out of 83
 


P. de la Peña, P. Domínguez and F. Barros
Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.
Pflugers Arch. – Eur. J. Physiol (2018) 470: 1069-1085
ISI Impact: 4.101                    Journal position in: Physiology, 13 out of 83


F. Barros, P. Domínguez and P. de la Peña
Relative positioning of Kv11.1 (hERG) K+ channel cytoplasmic domain-located fluorescent tags toward the plasma membrane.
Sci. Rep. (2018) 8: 15494.
DOI: 10.1038/s41598-018-33492-x
ISI Impact: 4.122                    Journal position in: Multidisciplinary, 12 out of 64


F. Barros, L.A. Pardo, P. Domínguez, L.M. Sierra and P. de la Peña
New structures and gating of voltage-dependent potassium (Kv) channels and their relatives: A multi-domain and dynamic question.
Int. J. Mol. Sci. (2019) 20: 248. DOI: 10.3390/ijms20020248
ISI Impact: 3.687                    Journal position in: Biochemistry
& Molecular Biology, 90 out of 292


F. Barros, P. de la Peña, P. Domínguez, L.M. Sierra and L.A. Pardo
The EAG voltage-dependent K+ channel subfamily: Similarities and differences in structural organization and gating.
Front. Pharmacol. (2020) 11: 411. DOI: 10.3389/fphar.2020.0041 
ISI Impact:  3.845                    Journal position in:  Pharmacology, 47 out of 300


S. Fernández-Villabrille,
E. Álvarez-González, F. Barros, P. de la Peña and L.M. Sierra
Influence of Kv11.1 (hERG) K+ channel expression on DNA damage induced by the genotoxic agent methyl methanesulfonate.

Pflugers Arch. – Eur. J. Physiol (2021) 473: 197-217 (DOI: 10.1007/s00424-021-02517-2)
ISI Impact: 4.101                    Journal position in: Physiology, 13 out of 83





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